The general outline of the story was for years the connecting factor the next part of the Doom series and has not changed significantly in the fourth installment. So we play again in the lone commando (ie. Doom marine), which is sent to a military base and research corporations UAC on Mars. It turns out that the result of the experiments, the researchers inadvertently launched the space-time portal through which to base leaked hordes of terrifying monsters. Following in the footsteps of enemies, the protagonist travels through different areas on Mars, then to get to hell and face the most powerful demons.